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How does Kamagra Polo affect blood flow to the genitals?
June 17, 2024
9:49 am
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Ronymeran
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Kamagra Polo, like other medications containing Sildenafil citrate, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). Here’s how it affects blood flow to the genitals:

Mechanism of Action: Sildenafil, the active ingredient in Kamagra Polo, inhibits PDE5 enzyme activity in the erectile tissue of the penis. Normally, PDE5 breaks down cyclic guanosine monophosphate (cGMP), which is responsible for smooth muscle relaxation in the blood vessels of the penis. By inhibiting PDE5, Sildenafil allows cGMP levels to increase, leading to relaxation of the smooth muscles and dilation of the blood vessels in the penis.

Increased Blood Flow: As the blood vessels in the penis dilate and relax, blood flow to the erectile tissue (corpora cavernosa) increases. This increased blood flow is crucial for achieving and maintaining an erection sufficient for sexual activity.

Enhanced Erection: When a man is sexually aroused, nerve signals trigger the release of nitric oxide (NO) in the erectile tissue of the penis. NO stimulates the production of cGMP, which in turn causes smooth muscle relaxation and vasodilation (widening of blood vessels). With inhibited PDE5 activity by Sildenafil, the effects of cGMP are prolonged, sustaining the dilation of blood vessels and maintaining an erection.

Effectiveness: Kamagra Polo, in its chewable tablet form, allows for faster absorption compared to traditional tablets. This can lead to quicker onset of action, typically within 30 minutes to an hour after ingestion.

Duration of Action: The effects of Kamagra Polo usually last for about 4 to 6 hours after ingestion. During this time, the enhanced blood flow to the genitals facilitates erectile function, enabling sexual intercourse.

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